Finally, race (Black, HR = 1.77), M stage (M1, HR = 2.93), surgery (non-MRM, HR = 0.74; MRM, HR = 0.60), CT status (Yes, HR = 0.46), tumor size (2–5 cm, HR = 0.91; >5 cm, HR = 1.48; Diffuse, HR = 1.39), ER (Positive, HR = 0.52), PR (Positive, HR = 0.64) and Her-2 (Positive, HR = 0.12) were confirmed as independent prognostic factors of IBC. This evidence concerns the gene ESR1 and neoplasm.