SAA1 and kidney disorder: Because renal tubular epithelial cells are studied to produce inflammatory mediators, such as cytokines and chemokines, and actively participate in acute inflammatory processes by effecting and directing leukocyte chemotaxis via the production of IL-828, these data suggest that SAA1 is actually involved in the early pathological process of kidney fibrosis and SAA1 serum levels might be useful assessing early stage human renal disease.