INS and benign prostatic hyperplasia: In addition, genes encoding insulin receptor 2 (InR2) (NLU008487.1) and insulin-like peptide 1 (ILP1) (NLU003562.3), and tumor-necrosis factor receptor-associated factor 5 (TNF5) (NLU005471.1) having crucial roles in the insect insulin signaling were found to be significantly upregulated in TN1-BPH as compared to the Mudgo-BPH.