We determined that 2.9% (CreLox HCC) to 15.2% [Tg(fabp10a:pt-β-cat) HCC] of hepatocytes from zebrafish β-catenin-driven HCC had detectable expression of two or more of the Wnt/β-catenin target genes axin2, mtor, glula, myca and wif1 (Fig. 7D and Table S16), and 0.8% (CreLox HCC) to 2.2% [Tg(fabp10a:pt-β-cat) HCC] of hepatocytes had detectable expression of three or more of these genes. Here, MTOR is linked to hepatocellular carcinoma.