HLA-DRB1 and systemic lupus erythematosus: HLA imputation and HLA-DRB1 amino acid-level analysis by Kim et al. [94] in 2013 hitherto identified the genomic elements that encode HLA-DRB1 amino acid positions 11, 13 and 26 at the epitope-biding groove of HLA-DR molecules which were associated with SLE.