Similarly, the oncogenic lncRNA TTN-AS1 facilitates expression of Snail1 and the actin-binding protein Fascin homolog 1 (FSCN1) by competitively binding miR-133b, resulting in ESCC cell proliferation, EMT, and metastasis [79]. The gene discussed is FSCN1; the disease is esophageal squamous cell carcinoma.