ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive: We herein designed and synthesized benzyl esters of different triterpenes (PT1–PT6) and the newly substituted benzyl esters of gypsogenin (GP1–GP5), based on our finding that 1c (benzyl ester of gypsogenin) has anti-ABL kinase and anti-CML activities [36].