As shown in Table 6 and Fig 5, MGMT promoter methylation was significantly associated with FIGO stage (OR = 2.81, 95% CI:1.79–4.41, p<0.001), but not with histological types (see Figure C in S1 File), histological grade (see Figure D in S1 File), HPV infection, therapeutic response, age and lymph node metastasis. The gene discussed is MGMT; the disease is metastatic malignant neoplasm in the lymph nodes.