APOC1 and familial pancreatic carcinoma: Knockdown of APOC1 expression inhibited proliferation and prompted apoptosis of pancreatic cancer cells.38 Overexpression of APOC1in breast cancer patients had diagnostic utility in distinguishing between triple‐negative breast cancer (TNBC) and non‐TNBC and thus was a potential prognostic factor for TNBC.39 APOC1 expression was increased in acute myeloid leukemia and played an oncogenic role in disease progression by mediating H3 acetylation regulated by ANP32A.40