LAMB2 and ovarian carcinoma: In the Hutmacher group, Kaemmerer et al. have indeed shown how they could be a suitable platform for the growth of ovarian cancer spheroids, investigating the effects of key tumor ECM components (laminin and hyaluronan) and matrix stiffness (ranging from 0.5 to 9 kPa) which both revealed significant responses in growth and treatments of organoids (Kaemmerer et al., 2014).