Conversely, the normal glandular tissue of breast is in the 1–45 kPa range (Cox and Erler, 2011; Ramião et al., 2016) and tumor ECM involves collagen I, IV, V, fibronectin, laminins, entactin, proteoglycans, and glycosaminoglycans (Gkretsi et al., 2015). Here, LAMB2 is linked to neoplasm.