Indeed, a recent prospective cohort study on 10,181 residents in Sihui city (27), southern China, showed that in non-NPC subjects, ever smokers were associated with higher odds of EBV seropositivity at baseline (VCA-IgA: adjusted OR = 1.40, 95% CI = 1.22–1.60; EBNA1-IgA: 1.58, 1.38–1.82), and in the 3–5 years of follow up (VCA-IgA: 1.68, 1.29–2.18; EBNA1-IgA: 1.92, 1.42–2.59). Here, CD79A is linked to nasopharyngeal carcinoma.