In addition, our results showing that the genetic alteration rate of SIRT3 was 2.4% and extensive deletion predominately occurred were in line with the findings that at least one copy of the SIRT3 gene was deleted in 40% of breast cancers and OC, and focal deletions of SIRT3 were especially frequent (Finley et al., 2011). This evidence concerns the gene SIRT3 and breast cancer.