We measured BAL CCL11 (eotaxin, an eosinophil chemoattractant), IL-23p19, IL-6, CXCL2 (pro-neutrophilic mediators), CCL20 (a lymphocyte chemoattractant), and IL-13 (known to prime smooth muscle cells for airway hyperreactivity). This evidence concerns the gene CCL20 and Irritability.