AQP1 or AQP2 or AQP3 or AQP4 antibody was substituted with PBS in the negative control, and the control slides included renal C, OM, and IM of a tissue section from O. cuniculus and L. yarkandensis in the immunohistochemistry experiment (Supplementary Figure S1). The gene discussed is AQP3; the disease is ocular melanoma.