Recent studies have suggested that NLRP3 inflammasome and downstream cytokines contribute to several types of kidney disease, including crystalline nephropathy (Mulay et al., 2013; Wang et al., 2018), obstructive nephropathy (Wang W. et al., 2015), and obesity-related kidney diseases (Ke et al., 2018). Here, NLRP3 is linked to kidney disorder.