ERBB2 and lung cancer: In the case of lung cancer, the elevated levels of mRNA fragments encoding HER2/neu, hnRNP-B1 (heterogeneous nuclear ribonucleoproteins B1) and 5Т4 (oncofetal trophoblast glycoprotein) were detected in blood (Kopreski et al., 2001; Fleischhacker et al., 2001; Sueoka et al., 2005).