In this way, the protein aggregates associated with FTD are the following: (i) tau protein (FTLD-tau); (ii) ubiquitin proteasome system (FTLD-UPS); (iii) transactive response of the DNA binding protein (FTLD-TDP); and (iv) fused in sarcoma, Ewing sarcoma, and TAF15 protein family (FTLD-FET) (Mackenzie et al., 2010; Irwin et al., 2015; Olney et al., 2017). This evidence concerns the gene MAPT and frontotemporal dementia.