MAPT and multiple system atrophy: In the diencephalon, a region in which tau-pathology in PSP is also abundant (Williams et al., 2007; Dickson et al., 2010), a significantly higher tracer uptake could be detected in PSP compared to PD and MSA-C, while tracer uptake also showed a trend toward significance in comparison to MSA-P (p = 0.015).