To determine whether altered hypothalamic gene expression as a result of maternal obesity is not only found for neurotrophic growth factors but also for their receptors, we quantified gene expression of TrkA, TrkB, TrkC, and p75Ntr in the hypothalamus of HFD and CO offspring at P21. The gene discussed is NTRK3; the disease is obesity due to melanocortin 4 receptor deficiency.