In consistent with the in vitro results (Additional file 1: Figure S6 and Fig. 6b), immunoblotting analysis of tumor homogenates showed that miR-141 mimics induced upregulation of p27 and E-cadherin, and downregulation of NRP-1, CDK2, cyclin E, Snail and N-cadherin (Additional file 1: Figure S8C). This evidence concerns the gene CDK2 and neoplasm.