Scientific literature reported that IL‐10 was related to the pathogenesis and development of coronary artery inflammation (Heeschen et al., 2003a), and have been considered a candidate gene for kind of cardiovascular diseases (CVD) (Liu, Hui‐Min, Yang, & Geriatrics, 2017), including vasculitis, cerebral infarction, atrial fibrillation, atherosclerotic, and stroke, but the results are still controversial. This evidence concerns the gene IL10 and Stroke.