Kaplan–Meier survival curves of sarcoma (Fig. 5b, left), colon adenocarcinoma (Fig. 5c, left), melanoma (Fig. 5d, left) and lung adenocarcinoma (Supplementary Fig. S5b, left) patients demonstrated that high expression of ZNF281 significantly correlates with poor prognosis only in patients treated with genotoxic agents. The gene discussed is ZNF281; the disease is colon adenocarcinoma.