Interestingly, the results showed that the IFNγ, TNFα, and IL-6 levels in the serum of the CAR-147 macrophage group were decreased compared with that of the control group (Fig. 2i), while the IL-12 and IFNγ levels were increased in tumour tissue samples from the CAR-147 macrophage-treated mice (Fig. 2i). This evidence concerns the gene IFNG and neoplasm.