As in cardiomyocytes, 15NG decreased HK-II in the mitochondrial fraction isolated from the 1321N1 human glioblastoma cell line (Fig. 1f) and induced an increase in mitochondrial Parkin but not PINK1 levels, while FCCP treatment increased both Parkin and PINK1. The gene discussed is PINK1; the disease is glioblastoma.