TGM2 and colorectal carcinoma: The fragmented TGM2 promoters were detected with qPCR to verify the potential ETS1-binding sites and among these, two recognition sites (−358 ~ −252, −186 ~ −13), specifically enriched by anti-Flag antibody compared with the IgG control, indicated TGM2 to be a direct target of transcript factor ETS1 in CRC (Fig. 5c).