Here, to investigate the relationship of triglyceride levels and the incidences of large areas of pancreatic necrosis in Gpihbp1−/− mice with large TRL particle sizes, we compared low triglyceride level Gpihbp1−/− mice (<2000 mg/dL, HTG1) with high triglyceride level mice (>2000 mg/dL, HTG2) on the severity of acute pancreatitis (Fig. 6a). The gene discussed is GPIHBP1; the disease is acute pancreatitis.