In the first set of experiments, the caspase 3/7 activity in Colo205 cancer cells treated with trimeric Nb283, tetrameric Nb284 and bispecific Nb28-113 mixed with Stx2aB5 pentamer were compared to the protease activity of these cancer cells after treatment with Apo2L/TRAIL. Here, TNFSF10 is linked to cancer.