Dendritic cells loaded with 18 potently inhibited regulatory T cells and activated myeloma-specific cytotoxic T lymphocytes, via the upregulation of heat shock protein (HSP) 90 and the cancer testis antigens MAGE-A3 and MAGE-C1/CT7 in myeloma cells [119]. This evidence concerns the gene MAGEA3 and plasma cell myeloma.