CD274 and non-small cell lung carcinoma: Moreover, Xing Y. et al. conducted a phase I clinical study evaluating the use of 99mTechnetium (99mTc) labeled Nbs for SPECT imaging of PD-L1 in patients with non-small cell lung cancer, showing that it is safe and feasible to image PD-L1 levels in the tumor as soon as 2 h after injection [29].