We reported that Hofbauer cells in first-trimester placentas from seropositive donors with HCMV neutralizing antibodies contain IgG and gB colocalized in cytoplasmic vesicles without HCMV IE1 protein in nuclei, indicating phagocytosis of virion-immune complexes without infection following transcytosis by the neonatal Fc receptor (FcRn) in syncytiotrophoblasts [33]. This evidence concerns the gene FCGRT and infection.