Fractionation of confluent 4T1 murine mammary cancer cells and normal murine mammary gland (NMuMG) cells into cytosol and membrane compartments showed that both p120 isoforms, as well as E-cadherin, α- and β-catenin are predominantly found in the membrane fraction (Figure 2A and Figure S2A). The gene discussed is CDH1; the disease is breast cancer.