Considering the differential effects of p120-1 and p120-3 on invasion, proliferation and metastasis [21,30,34], the high expression of p120-3 and varying levels of p120-1 in different stages of metastasis may play important roles in controlling tumor progression, and this may be partially regulated by p120 isoform-specific downstream interaction partners. Here, CTNND1 is linked to neoplasm.