These results suggest that TMZ might be less effective in inhibiting tumor cell filtration than inhibiting tumor cell proliferation, as shown in Figure 1C. Figure 6C further shows glioblastoma cell migration to the contralateral brain region, indicated with a yellow arrow in Figure 6A. In the PBS-treated group, a number of CD44-positive glioblastoma cells were observed in the corpus callosum of the contralateral hemisphere. This evidence concerns the gene CD44 and glioblastoma.