Nevertheless, MRP-1 salivary efflux function can be potentially involved in oral mucositis produced by methotrexate [17], doxorubicin [18], cyclophosphamide [19] (via mediating the excretion of the drugs from blood into saliva) or treatment of bacterial pathogens within the gland (ciprofloxacin) [20]. Here, ABCC1 is linked to oral mucositis.