Rather, reports have indicated a role for another estrogen receptor, ERβ, in PDAC.36, 37 However, the studies which determined that ERβ is expressed in PDAC used antibodies which have been recognized as problematic.28 Current TCGA data, based on unbiased large‐scale RNA‐Seq of clinical tumor specimens, do not support the expression of ERβ in PDAC. This evidence concerns the gene ESR2 and neoplasm.