Abnormal expression of TIMP2 has been implicated in growth and invasion of multiple malignant tumors.18 Several upstream factors have been reported to mediate tumor progression and metastasis through the TIMP2.19, 20, 21 For instance, EZH2 was found to promote metastasis via TIMP2 signaling pathway in EOC.20 However, the relationship between lncRNA ABHD11‐AS1 and TIMP2 has not been studied in detail. This evidence concerns the gene EZH2 and cancer.