DENV–NS3‐specific CD8+ T cells of patients with DF produced significantly more (P = .045) IFNγ (median = 0.28; IQR, 0%‐0.51%) compared to those of patients with DHF (median, 0; IQR, 0%‐0.24%) (Figure 1A). This evidence concerns the gene CD8A and dengue disease.