To analyze the association between HOXB7 expression and cisplatin sensitivity in ESCC cells, we examined HOXB7 expression on the levels of mRNA and protein in four ESCC cell lines (KYSE150, KYSE180, KYSE70 and KYSE450) (Fig 1a), then CCK‐8 assay was performed to investigate the effect of cisplatin on cell viability. The gene discussed is HOXB7; the disease is esophageal squamous cell carcinoma.