Consistent with our findings, a previous study concluded that the up‐regulation of VEGFA in podocytes results in changes to glomerular selectivity and filtration, loss of podocytes and a decline in renal function in cases of DN.29 Accumulating studies have highlighted the regulatory effect of miRNAs on the expression of MCP‐1, TGF‐β1 and TNF‐α. This evidence concerns the gene TNF and liver dysplastic nodule.