Previous evidences from cross‐sectional studies demonstrate an inverse relationship between hyperglycemia prevalence and vitamin D status.4, 12 Conversely, longitudinal studies show that low status of vitamin D is also a predictor for type 2 diabetes (T2DM) incidence.13, 14 Further clarity to whether vitamin D together with resistance from insulin is associated causally or whether they institute 2 autonomous features of patients with diabetes is needed. This evidence concerns the gene INS and type 2 diabetes mellitus.