TNF and Sepsis: As a marker of inflammation, the role of P-selectin in determining sepsis patients in the emergency department has been reported sporadically.[19] Hence, IL-3, IL-4, IL-12p70, IL-17A, MIP-1β, IFN-γ, and P-selectin, together with 2 classic inflammatory markers, TNF-α and NLR, were selected for study.