DCN and neoplasm: Decorin is a prototype small leucine-rich proteoglycan; it functions in collagen angiostasis, fibrillogenesis, wound repair, tumor growth, autophagy, and inflammation.[27] In this study, Decorin is the only autoantibody whose concentration is higher in both TPE-Serum and TPE compared with MPE-serum and MPE, respectively, and it may play a role in the pathogenesis of TPE.