Several studies indicated that the MTHFR 677C>T polymorphism, especially in the homozygous state, could be associated with a milder clinical phenotype of hemophilia (Ahmed, Kannan, Choudhry, & Saxena, 2003; Ghosh, Shetty, & Mohanty, 2001; Nowak‐Göttl et al., 2003). The gene discussed is MTHFR; the disease is hemophilia.