SYP and neoplasm: In addition, knockdown of both Syp and Imp in prosRNAi, SypRNAi, ImpRNAi tumors arrested tumor growth in adults (Figure 6F and Figure 6—figure supplement 2), and tumors lacked or exhibited low levels of Chinmo (Figure 6—figure supplement 2) demonstrating that, even in the absence of Syp, Imp is essential for Chinmo expression in tumors and that is required for their continuous growth.