Among dystroglycanopathies, allelic FKRP mutations are the more prevalent and cause a wide spectrum of clinical severities that range from the mild late‐onset limb‐girdle muscular dystrophy without neurological deficits (e.g. LGMD2I) to congenital muscular dystrophy with severe CNS abnormalities (e.g. Walker–Warburg syndrome) 39. The gene discussed is FKRP; the disease is neuromuscular disease caused by qualitative or quantitative defects of alpha-dystroglycan.