TP53 and cancer: This cancer profile is more similar to the Atm−/− animals which also developed lymphomas in the majority of animals (80%, Table 1), in contrast Smg1gt/+ mice who developed a combination of lymphomas and papillary lung adenocarcinomas as we have described previously (Table 1).12 We performed a similar experiment crossing Smg1gt/+ mice to p53−/− mice.