For instance, lncRNA ZFAS1 is overexpressed in hepatocellular carcinoma and acts as oncogene by binding miR‐150, ZFAS1 promotes gastric cancer cell growth by repressing KLF2 and NKD2 expression, ZFAS1 is an unfavourable prognostic factor for glioma patients and promotes tumour cell malignant progression by the activation of Notch signalling pathway, and many others.24, 26, 27 Up to date, ZFAS1 has been demonstrated dysregulated and involved in several different cancers functions as oncogene; however, the possible biological role and prognostic capacity of ZFAS1 in CCA are still ambiguous. Here, ZFAS1 is linked to cholangiocarcinoma.