When PERP knockdown followed by treatment with MY1WT in dGCs, there is an opposite trend emerged of the mRNA expression level of TNF-α (P <0.05) (Fig. 3G, Table S2), however, overexpression of PERP or knockdown PERP showed no significant mRNA level change of IL-6, IL-1β, TNF-α, and IFN-γ during MY1ΔsipC infection (Figs. 3F and 3H, Table S2). The gene discussed is TNF; the disease is infection.