BSG and neoplasm: Recently, a growing body of evidence has suggested that the pro-tumoral action of CD147 is partly due to the interaction between two monocarboxylate transporters, MCT1 and MCT4, which accelerates tumor cell glycolysis by increased glucose uptake, lactate efflux, and the production of adenosine triphosphate (Huang et al., 2015; Li et al., 2016; Marchiq et al., 2015; Walters, Arendt & Jelinek, 2013).