VCAM1 and cancer: This triggers the activation of integrins from the cancer cells allowing their firmer adhesion to members of the Ig‐CAM family such as ICAM and VCAM‐1, initiating the transendothelial migration and therefore the extravasation process.17 VCAM‐1 is therefore thought to play a key role in the process of malignant progression and its presence studied in terms of impact on cell migration.19