The STIM1 protein was mainly confined to the cytoplasm of epithelial cells, which exhibited 76.99% (271/352) positive staining in NSCLC cases vs. 18.72% (35/187) in benign pulmonary conditions (P = 0.00001; Figure 1(b,d)). This evidence concerns the gene STIM1 and non-small cell lung carcinoma.